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March 2026

Polymer Cuff Electrodes Prove Viable for Selective Peripheral Nerve Stimulation

Polymer Cuff Electrodes Prove Viable for Selective Peripheral Nerve Stimulation

A team at Imperial College London has validated fully polymeric conductive elastomer nerve cuffs as effective alternatives to metallic electrodes for fascicular-selective peripheral nerve stimulation. Published in the Journal of Neural Engineering in 2026, the study combined ex vivo experiments on rat sciatic nerves with microCT-informed computational modelling, achieving selectivity indices above 0.65 across all three target fascicles. Advent Research Materials supplied the precision PTFE-insulated silver wire used as electrical interconnects within the electrode assembly.

Tungsten Microelectrodes Help Map How Early Alzheimer’s Pathology Spreads Through the Brain

Tungsten Microelectrodes Help Map How Early Alzheimer’s Pathology Spreads Through the Brain

A 2026 study in The Journal of Physiology from the University of Castilla-La Mancha and Pablo de Olavide University tracks how early amyloid-β accumulation disrupts brain circuit activity across connected regions. Using Advent 50 μm tungsten microelectrodes implanted in the posterior parietal cortex, researchers revealed a precise temporal sequence: hippocampal dysfunction emerges within hours, spatial memory deficits by day one, and measurable cortical oscillatory disruption by day three.

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